This report presents the results of our self-initiated audit of the Efficiency of Operations at the Indianapolis Processing and Distribution Center (P&DC) in Indianapolis, IN (Project Number 22-080). We conducted this audit to provide U.S. Postal Service management with timely information on operational risks at this P&DC. We judgmentally selected the Indianapolis P&DC based on a review of overtime, penalty overtime, late, extra, and cancelled trips by Postal Vehicle Service (PVS) and Highway Contract Route (HCR) drivers, and overall scanning performance. The Indianapolis P&DC is in the Westshores Division and processes letters and flats; and it services multiple 3-digit ZIP Codes in urban and rural communities.